Influence of Systematically Varied Nano-Scale Topography on Cell Morphology and Adhesion

FRET measurements of cell-traction forces and nano-scale clustering of adhesion ligands varied by substrate stiffness.

The mechanical properties of cell adhesion substrates regulate cell phenotype, but the mechanism of this relation is currently unclear. It may involve the magnitude of traction force applied by the cell, and/or the ability of the cells to rearrange the cell adhesion molecules presented from the material. In this study, we describe a FRET technique that can be used to evaluate the mechanics of c...

Structural and functional analysis of cell adhesion and nuclear envelope nano-topography in cell death

The cell death mechanisms of necrosis and apoptosis generate biochemical and morphological changes in different manners. However, the changes that occur in cell adhesion and nuclear envelope (NE) topography, during necrosis and apoptosis, are not yet fully understood. Here, we show the different alterations in cell adhesion function, as well as the topographical changes occurring to the NE, dur...

Cell adhesion, morphology and biochemistry on nano-topographic oxidized silicon surfaces.

Manipulating an incorporated scaffold to direct cell behaviors play a key role in tissue engineering. In this study, we developed novel nano-topographic oxidized silicon nanosponges capable of being modified with various chemicals of a few nm in thickness to gain further insight into the fundamental biology of cell-environment interactions in vitro. A wet etching technique was applied to fabric...

the influence of social and cultural capital on efl students critical thinking skills

the major aim of this study was to investigate the relationship between social and cultural capital and efl students’ critical thinking skills. this study takes this relationship in to account to see if people with different sociocultural status are different regarding their critical thinking skills. to this end, 160 university students majoring in english language and literature, english trans...

Immersion scatterometry for improved nano-scale topography measurements